Association comprises: agomelatine (N-[2-(7-methoxy-1-naphtyl)ethyl]acetamide) or its hydrate, crystalline, acid or base salts and thymoregulating agent. ACTIVITY : Hypnotic Antidepressant Cardiovascular-Gen Neuroleptic Anorectic Gastrointestinal-Gen CNS-Gen. MECHANISM OF ACTION : Melatoninergic receptor system agonist Hydroxytryptamine receptor antagonist.