Vernon G. Wong;Louis L. Wood;Carol Wood;Glenn T. Huang
发明人:
Vernon G. Wong,Louis L. Wood,Glenn T. Huang
申请号:
US14124631
公开号:
US09814773B2
申请日:
2012.06.11
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides for injectable pharmaceutical sustained release formulations for delivery of active agents, particularly therapeutic proteins, to the eye. The formulations are biocompatible, biodegradable sustained release formulations comprising low-solubility liquid excipients and relatively small amounts (less than about 10%) of biocompatible, biodegradable polymer such as PLA or PLGA polymers. A unit dose of 5 μL to 100 μL of the formulation provides for sustained release of the agent for at least 14 days.