Approaches for evaluating fluid flow based on fluorescent sensing is disclosed. In one approach, a nanoparticle injector is configured to inject nanoparticles into fluid flowing through a conduit. A detector is configured to determine a presence of the nanoparticles in the flow of the fluid. The detector can include a radiation source configured to irradiate the fluid with a target radiation and a fluorescent meter configured to measure an amount of fluorescence emitted from the fluid irradiated with the radiation. A control unit is configured to determine the flow of the fluid in the conduit as a function of the measured amount of fluorescence.