Claim 1: a compound of the formula (1) or a pharmaceutically acceptable Salt thereof,Where: r¹ heterociclilo is 3 to 10 members r⁵a or cycloalkyl substituted by c₃₋₈ replaced by r⁵b,Where the heterociclilo 3 to 10 members and the c₃₋₈ cycloalkyl optionally substituted by one or more further r⁶ each is independently R² F, Oh, alkyl c₁₋₄, fluoroalquilo c₁₋₄,C₁₋₄ alkoxy or fluoroalcoxi c₁₋₄ r²a and r²b are independently h, F, Oh, c₁₋₄ fluoroalquilo c₁₋₄ alkyl, alkoxy, or c₁₋₄ fluoroalcoxi c₁₋₄ where each alkyl c₁₋₄ and fluoroalquilo c₁₋₄ in R²,R²a r²b replaced optionally independently by Oh, c₁₋₄ alkoxy or fluoroalcoxi c₁₋₄ r³ is H, F, CL, nh₂, alkyl or c₁₋₄ fluoroalquilo c₁₋₄,Where the alkyl c₁₋₄ and fluoroalquilo c₁₋₄ optionally replaced by Oh, CN, c₁₋₄ alkoxy, fluoroalcoxi c₁₋₄, conh₂ and COOH r⁴ is H, alkyl or c₁₋₂ fluoroalquilo c₁₋₂ r⁵a is so₂r⁷, so₂nr⁸r⁹,Nhso₂r⁷ or nhso₂nr⁸r⁹ r⁵b is nhso₂r⁷ or nhso₂nr⁸r⁹ each is independently r⁶ F, Oh, c₁₋₄ fluoroalquilo c₁₋₄ alkyl, alkoxy, or c₁₋₄ fluoroalcoxi c₁₋₄ r⁷ is alkyl c₁₋₄, fluoroalquilo c₁₋₄,- L - (cycloalkyl c₃₋₈) - L - (heterociclilo 5 to 6 Members) or - L - (heteroaryl 5 to 6 Members) and r⁸ r⁹ are independently h, alkyl c₁₋₄, fluoroalquilo c₁₋₄, - L - (c₃₋₈ cycloalkyl)- L - (heterociclilo 5 to 6 Members) or - L - (heteroaryl 5 to 6 Members) or r⁸ and r⁹ can be taken together with the nitrogen Atom to which Unite to form a heterociclilo 5 to 6 membersWhere each c₁₋₄ and fluoroalquilo c₁₋₄ in r⁷ alkyl, optionally r⁸ and r⁹ is replaced by Oh, c₁₋₄ fluoroalcoxi c₁₋₄ alkoxy, or so₂me, and each c₃₋₈ cycloalkyl,Heterociclilo 5 to 6 members and heteroaryl of 5 to 6 members in r⁷, r⁸ and optionally r⁹ is replaced by alkyl or alkoxy c₁₋₄, Oh, c₁₋₄ fluoroalcoxi c₁₋₄ l is a Union or alquileno c₁₋₄,Where alquileno c₁₋₄ alkoxy optionally replaced by Oh, c₁₋₄ or fluoroalcoxi c₁₋₄ p is 0, 1, 2, 3 or 4 Q is 0, 1, 2 or 3 and R is 0, 1 or 2.Reivindicación 1: Un compuesto de la fórmula (1), o una sal farmacéuticamente aceptable del mi
