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Peptides that suppress differentiation of hematopoietic stem cells or hematopoietic progenitor cells and uses thereof
专利权人:
国立大学法人九州大学
发明人:
杉山 大介
申请号:
JP2011534289
公开号:
JP5791506B2
申请日:
2010.09.29
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
The present invention provides a novel peptide that can be effectively used to produce or grow tissue-specific stem cells or tissue-specific progenitor cells in vitro. The peptide of the invention is a peptide having an amino acid sequence consisting of the amino acid residues set forth in SEQ ID NO:1, or an analog thereof. A feature of the peptide of the invention is having at least one of the following effects: (1) an effect of inhibiting differentiation of hematopoietic stem cells or hematopoietic progenitor cells into myeloid cells, (2) an effect of promoting amplification of mesenchymal stem cells, and (3) an effect of inducing hematopoietic stem cells from pluripotent stem cells.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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