PROBLEM TO BE SOLVED: To provide a novel disubstituted 1,2,4-triazine compound that has aldosterone synthase inhibitory activity and is useful for the prevention and/or treatment of various diseases or symptoms caused by aldosterone, or a pharmaceutical composition comprising pharmacologically acceptable salt thereof as an active ingredient.SOLUTION: The present invention provides a compound represented by general formula [I] [Ris a group represented by the formula (A-1) (where ring Ais an optionally substituted cycloalkyl group and the like) and the like, Ris a monocyclic cycloalkyl group and the like], or a pharmaceutical composition comprising pharmacologically acceptable salt thereof as an active ingredient.SELECTED DRAWING: None
