Assembly (40) for endoscopically securing gastrointestinal tissue folds, comprising a first tissue anchor (41) and a second tissue anchor (42), a first suture thread part (43 (P)) and a second suture thread part (43 (L), 44), each of the first and second thread parts having a connected end and a free end opposite the connected end. The first thread part and the second thread part are tied to each other through a sliding knot (15), such that the first thread part forms a post (P) of the sliding knot along which the sliding knot is arranged to slide during tightening of the assembly and such that the second thread part wraps around the post to create the sliding knot. The first thread part extends from the first anchor (41) to past the sliding knot (15) where the first thread parts free end (132) forms a post free end (44), and the second thread part extends from the second anchor (42) to past the sliding knot (15) where the second thread parts free end is free, such that the sliding knot is interposed between the first and second anchors. The first or the second anchor (32, 42) comprises a knot retaining through hole (121, 1 21), wherein the post free end (132, 44) slidingly passes through the knot retaining through hole (121, 121), the knot retaining through hole having a size preventing the sliding knot (15) to pass through the knot retaining through hole, such that the anchor can be used as a knot retainer during tightening.Linvention concerne un ensemble (40) pour fixer des plis de tissu gastro-intestinal par voie endoscopique, comprenant un premier ancrage de tissu (41) et un second ancrage de tissu (42), une première partie fil de suture (43 (P)) et une seconde partie fil de suture (43 (L), 44), chacune des première et seconde parties fil ayant une extrémité reliée et une extrémité libre opposée à lextrémité reliée. Le première partie fil et la seconde partie fil sont liées lune à lautre par un nœud coulissant (15), de telle sorte que la première partie fil for
