The United States of America as represented by the Department of Veterans Affairs
发明人:
Kishore Bellamkonda K.,Zhang Yue,Ecelbarger Carolyn M.
申请号:
US201314438854
公开号:
US10107795(B2)
申请日:
2013.10.25
申请国别(地区):
美国
年份:
2018
代理人:
Adriano & Associates
摘要:
Blunting the activity of the P2Y2 receptor results in a resistance to diet-induced obesity, an increased metabolic rate, and a better glucose tolerance. Compounds that inhibit the puringeric P2Y2 receptor are useful for treating disorders associated with diabetes, treating obesity, and increasing metabolism (e.g., fatty acid metabolism).