PROBLEM TO BE SOLVED: To provide an anagenesis base material excellent in invasiveness of a cell, and can efficiently prevent leakage of a cell from the anagenesis base material, for promoting reproduction of a tissue.SOLUTION: Provided is the anagenesis base material formed of a nonwoven fabric which is formed of a living matter absorption material, the anagenesis base material comprises a lamination structure formed of a layer of a nonwoven fabric whose average pore diameter is 20-50 μm, and a layer of a nonwoven fabric whose average pore diameter is 5-20 μm.SELECTED DRAWING: None