Peter Jeffery LEEDMAN,Keith Michael GILES,Ann Mary BROWN
申请号:
US14436638
公开号:
US20150366895A1
申请日:
2013.10.18
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates generally to methods and compositions for the treatment of cancers expressing the type 1 insulin-like growth factor receptor (IGF1R) or a constituent of an IGF1R signaling pathway, in particular melanoma, using the microRNA miR-7-5p. Also provided are methods for increasing the sensitivity of such cancers to therapeutic agents.