Karine Lelu-Santolaria,Roland Kratzer,Perrine Martin
申请号：
US16339417
公开号：
US20190328869A1
申请日:
2017.10.10
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides an immunotherapeutic composition for use in combination with one or more MDSC (Myeloid-derived suppressor cells) modulator(s) and a kit of parts comprising such components as well as methods using such components in combination. The invention also provides the use of Phosphodiesterase-5 (PDE5) inhibitors for reversing immunosuppression in chronic infectious diseases. The invention is of very special interest in treating or preventing diseases, especially chronic infectious diseases such as hepatitis B.
