Song Li,Xiaoqian Xu,Guoming Zhao,Lili Wang,Hua Guan,Junhai Xiao,Wu Zhong,Zhibing Zheng,Yunde Xie,Xingzhou Li,Xiaokui Wang,Xinbo Zhou,Hongying Liu
申请号:
US13380270
公开号:
US08802669B2
申请日:
2010.05.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are dihydropyrimidine compounds and preparation methods, pharmaceutical compositions and uses thereof. Specifically, the compounds described herein in general formula (I), or their isomers, pharmaceutically acceptable salts or hydrates are provided, wherein each variable has the meaning as defined in the description. Also provided are a process for preparing the compounds of the general formula (I), the use of the compounds, an isomer thereof, a pharmaceutically acceptable salt thereof or a hydrate thereof as a medicament, in particular as a medicament for the treatment and/or prevention of Hepatitis B.