A tubeset module includes one or more elements of a negative pressure wound therapy (“NPWT”) system, such as a valve, a calibrated leak, a pressure sensor, etc. The tubeset module may communicate with a controller of the NPWT system via a communications interface provided by the tubeset module. The communication between the tubeset module and the controller may be used to fully automate one or more processes involving the operation of the components of the NPWT system included in the tubeset module, allowing the NPWT system to, e.g. estimate a wound site volume, estimate a volume of fluid to be instilled, monitor wound healing progression, etc. without requiring any user interaction or involvement. The tubeset module may be defined by one or more housing elements. The tubeset module may be incorporated into any of the tubing, fluid canister, wound dressing and/or therapy device housing components of the NPWT system.
