Construction of oncolytic herpes simplex viruses (oHSV) obligate vector and constructs for cancer therapy

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专利权人:

Immuno Vir Co.; Limited

发明人:

Zhou, Grace Guoying,Chen, Xiaoqing,Liu, Xianjie

申请号：

AU2016403583

公开号：

AU2016403583A1

申请日:

2016.04.22

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

An obligate oHSV vector comprising modified viral DNA genome is provided. A recombinant oHSV-1 construct comprising the obligate oHSV vector and a heterologous nucleic acid sequence encoding an immunostimulatory and/or immunotherapeutic agent is also provided. Compositions comprising the recombinant oHSV-1 construct can be used for treating cancers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/