QUINAZOLINE BASED EGFR INHIBITORS

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专利权人:

CURIS; INC.

发明人:

CAI, XIONG,蔡雄,蔡雄,QIAN, CHANGGENG,钱长庚,錢長庚

申请号：

TW096133860

公开号：

TWI399204B

申请日:

2007.09.11

申请国别(地区):

TW

年份:

2013

代理人:

摘要：

The present invention relates to quinazoline containing zinc-binding moiety based derivatives that have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and their use in the treatment of EGFR-TK related diseases and disorders such as cancer.本發明係關於含鋅結合位之喹唑啉系衍生物,其具有增強及無法預期之對於表皮生長因子受體酪胺酸激酶(EGFR-TK)之抑制劑的性質,以及使用該等於治療EGFR-TK相關疾病以及病症,例如癌症。

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/