Respect to particulate material for controlled release of the active ingredient, contain an inorganic mineral filler and a combination of one or more active ingredients except nicotine particulate matter, the present invention is absorbed reversibly to inorganic mineral fillers active ingredient and adsorbed or /, BET specific surface area of the inorganic mineral filler greater than about 15m 2 / g, the BET specific surface area is measured according to ISO9277. The present invention is particularly useful for controlled release of the active ingredient.本発明は活性成分を放出制御するための粒状物質に関し、該粒状物質はニコチンを除く1以上の活性成分の組み合わせおよび無機鉱物充填剤を含み、該活性成分は無機鉱物充填剤に可逆的に吸収および/または吸着され、無機鉱物充填剤のBET比表面積は約15m2/gを上回り、該BET比表面積はISO9277に従って測定される。本発明は活性成分の放出制御に特に有益である。
