The various embodiments of the subject invention included herein provide devices, systems and methods for aiding the regrooming or refolding of balloons upon deflation. The scope of the inventions in this specification includes methods and devices that reduce the profile of balloons after deflation, reduce or eliminate wings, high-points, irregularities, bunching, thickening, and the like, and facilitate passage of a deflated balloon through a body void or lumen, or through a medical device such as a guide catheter, guide sheath, femoral or radial introducer sheath, and the like.