The present discloses a kind of paclitaxel steroid compound. Paclitaxelsteroid compound is composed of paclitaxel and steroid lipid molecule bynonchemical bonding reaction, the molar ratio of paclitaxel and steroid is1:0.2-4, preferably 1:0.25-2. The invention also discloses the preparation ofpaclitaxel steroid compound and preparation of submicron emulsion,self-microemulsifying system and oral preparations. Steroid compound hasgreatly improved the paclitaxel solubility in oil phase and also provides agood intermediate carrier for new emulsion with high encapsulationefficiency, good safety and stable quality and for oral preparations with highbioavailability.
