The invention relates to extrudates containing at least one pharmaceutically active substance in the form of needles, wherein the ratio of the particle size of the needle-shaped pharmaceutically active substance to the strand diameter is at least 1:15, and the use of these extrudates for the production of medicaments.本發明係關於一種含有至少一針形醫藥活性物質的擠製物,其中該針形醫藥活性物質對絞線直徑的粒徑比例為至少1:15,以及這些擠製物於製造藥物的用途。