Use of Quaternary Pyridinium Salts as Vasoprotective Agents

• 收藏
• 分享

专利权人:

Pharmena Spólka Akcyjna (Pharmena S.A.)

发明人:

Jerzy GEBICKI,Stefan CHLOPICKI

申请号：

US14598888

公开号：

US20150133508A1

申请日:

2015.01.16

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The invention relates to the use of quaternary pyridinium salts of formula (I),wherein R is NH2, CH3, or N(H)CH2OH group, and X is pharmaceutically acceptable counterion, for the preparation of vasoprotective agent for the treatment or prevention of conditions or diseases associated with dysfunction of vascular endothelium, oxidative stress, and/or insufficient production of endothelial prostacyclin PGI2, in particular but not exclusively if the above coincides with hypercholesterolemia, hypertriglyceridemia or low HDL level.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/