SON, JUN HOKR,손준호,PARK, TAE SOONKR,박태순,HWANG, JU YOUNGKR,황주영,KIM, DONG HEEKR,김동희,HWANG, EUN YOUNGKR,황은영,PARK, HYE JINKR,박혜진,PARK, JIN YOUNGKR,박진영,KIM, JI HYANGKR,김지향
申请号:
KR1020120119677
公开号:
KR1020140056487A
申请日:
2012.10.26
申请国别(地区):
KR
年份:
2014
代理人:
摘要:
A persimmon calyx extract or a compound isolated from the same of the present invention executed a strong whitening activity during tyrosinase enzyme and melanin synthesis experiments related to whitening efficacy and also executes a strong inhibitory activity for biosynthesis of procollagen type I, MMP-1 activity, and TIMP-1 activity associated with the creation of wrinkles thereby can be valuably used as a pharmaceutical and cosmetic composition for skin whitening and wrinkle mitigation.COPYRIGHT KIPO 2014본 발명은 감꼭지 추출물 또는 이로부터 분리된 화합물은 미백효능과 관련된 티로시나제 효소 및 멜라닌 합성 실험에서 강력한 미백활성을 나타냈을뿐만 아니라, 주름생성과 관련된 프로콜라겐 type Ⅰ생합성과 MMP-1 활성, TIMP-1의 활성 등에 강력한 억제활성을 나타내 미백 및 주름개선용 약학 및 화장료 조성물로 유용하다.