Stephanie Lynn Swarner,Leah Johnson,Robert F. Praino, JR.,Phillip Gregory Durham,Mark E. Kleiman,Ginger Denison Rothrock,Ariane van der Straten Ponthoz
申请号:
US15890171
公开号:
US20180235900A1
申请日:
2018.02.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The medical devices of the present disclosure are filled reservoirs such as a cylinder comprised of a polymer film which contains a reservoir of active agent, plus excipient, in some cases, for disease prevention, treatment, and/or contraception. The polymer film is permeable to the active agent after subcutaneous implantation of the device into a body. The cylinder is comprised by the lamination of one or two polymer films which are ultrasonically welded to contain the drug material. The use of an ultrasonic welding process enables sealing of the polymer films to create the closed cylinder. The medical device is useful for long term disease prevention, such as prevention of HIV infection.