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Small peptides and methods for inhibiting mucus release into airways
专利权人:
John C. Houck;Mary MacDonald, legal representative;James Clagett
发明人:
John C. Houck,James Clagett
申请号:
US11942202
公开号:
US08097589B2
申请日:
2007.11.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucus release into airways of a patient, a method for blocking IgE activation of a lymphocyte, a method for stabilizing the cell membrane of a lymphocyte, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
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