Glenn D. Prestwich;Wanjian Jia;Won Yong Lee;Lindsi McCoard;Siam Oottamasathien, VIII
发明人:
Glenn D. Prestwich,Siam Oottamasathien, VIII,Wanjian Jia,Lindsi McCoard,Won Yong Lee
申请号:
US14006771
公开号:
US20140343011A1
申请日:
2012.03.23
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Described herein are methods for treating or preventing urological inflammation in a subject comprising administering to the subject an effective amount of a compound comprising a. a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and at least one primary C-6 hydroxyl position of an N-acetyl-glucosamine residue comprising an alkyl group or fluoroalkyl group; b. a partially or fully sulfated hyaluronan or the pharmaceutically acceptable salt or ester thereof, or a combination thereof.