The present invention provides methods and compositions for treating leukemia by cyclohexenone compounds. Leukemia (leukaemia) is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature while blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases. In turn, it is part of the even broader group of diseases affecting the blood, bone marrow, and lymphoid system, which are all known as hematological neoplasms.La presente invención provee métodos y composiciones para tratar leucemia mediante compuestos de ciclohexenona.