Roland K. STRONG,Colin CORRENTI,Leonidas STAMATATOS,Andrew McGUIRE
申请号：
US15561438
公开号：
US20180117140A1
申请日:
2016.03.24
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Multimerized human immunodeficiency virus (HIV) envelope glycoproteins are described. The envelope glycoproteins are multimerized Engineered and multimerized human immunodeficiency virus (HIV) envelope glycoproteins are described. The envelope glycoproteins can be multimerized using a heptamerization domain such as a C4b binding protein multimerization domain or a ferritin fusion. The engineered and multimerized envelope glycoproteins can derived from glycoprotein 120 (gp120) and can used as an HIV vaccine.
