Balsalazide formulations and manufacture and use thereof

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专利权人:

SALIX PHARMACEUTICALS INC.

发明人:

LOCKHART JOSEPH,SWANSON BROCK,JOHNSON LORIN

申请号：

NZ60374406

公开号：

NZ603744A

申请日:

2006.08.24

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

Disclosed is a pharmaceutical preparation comprising two daily doses of about 6.6 grams per day of balsalazide or a pharmaceutically acceptable salt, solvate, or clathrate thereof made by the process, comprising: granulating a balsalazide disodiumfeed powder and one or more excipients to form granules； sizing the granules； blending the granules for about 20 minutes to form a powder blend； and encapsulating the powder blend, wherein the encapsulated powder blend may optionally be polished after encapsulation.

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