Disclosed herein are methods and compositions for the intravenous administration of fumarates for the treatment of neurological diseases, such as stroke, amyotrophic lateral sclerosis, Huntington’s disease, Alzheimer’s disease, Parkinson’s disease, and Multiple Sclerosis.本文揭示用於靜脈內投與反丁烯二酸酯以治療神經疾病,諸如中風、肌萎縮性側索硬化、亨廷頓氏病(Huntington's disease)、阿茲海默氏病(Alzheimer’s disease)、帕金森氏病(Parkinson’s disease)及多發性硬化之方法及組合物。