Thea Norman;G. Todd Milne;Mark G. Currie;Shalina Mahajan-Miklos
发明人:
Mark G. Currie,Shalina Mahajan-Miklos,G. Todd Milne,Thea Norman
申请号:
US12788979
公开号:
US08110553B2
申请日:
2010.05.27
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention features compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), Crohn's disease, ulcerative colitis, Inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation (post-operative ileus), and constipation associated with neuropathic disorders as well as other conditions and disorders using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.