Theodoros Zanos,Todd Levy,Emily Battinelli,Kevin J. Tracey,Chad E. Bouton,Sangeeta Chavan,Harold Silverman
申请号:
US16605818
公开号:
US20200179600A1
申请日:
2018.04.19
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure relates to systems, methods and devices to monitor, diagnose and/or treat diseases or disorders comprising a calibration phase and a real-time diagnostic, treatment or monitoring phase, the calibration phase correlating a plurality of nerve activity measurements from a chronically implanted electrode in a subject with a plurality of concurrent measurements of levels of cytokines and/or glucose in the blood to obtain a functional relationship between blood cytokine and/or glucose levels and vagus nerve activity, and the diagnostic, treatment or monitoring phase analyzing the subject's real-time vagus nerve activity in accordance with the previously obtained functional relationship to initiate a treatment method.