WANG, HOON SIK,왕훈식,OH, JIN SUB,오진섭,PARK, JUN SANG,박준상
申请号：
KR1020110057227
公开号：
KR1020120137998A
申请日:
2011.06.14
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A soft capsule formulation containing sustained release tamsulosin salts-containing granules and finasteride-containing powder is provided to ensure stability in a humid place.CONSTITUTION: A soft capsule formulation contains sustained release tamsulosin salts-containing granules and finasteride-containing powder. The amount of tamsulosin hydrochloride and finasteride is 0.1-0.8 mg and 1-5 mg, respectively. A method for manufacturing the sustained release tamsulosin particles comprises: a step of coating an inactive core with a drug and coating the upper end of the core with water-insoluble polymers of ethyl cellulose a step of additionally coating the upper end with enteric polymers of methacrylic copolymer type C and mixing sustained release particles without enteric coating and enteric sustained release particles.COPYRIGHT KIPO 2013[Reference numerals] (AA) Drug elution(%) at 45 minutes (BB) United States Pharmacopeia standard (CC) Comparative embodiment 1 (DD) Embodiment 3 (EE) Time(months)본 발명은, 서방형 탐스로신염산염 함유 과립 및 피나스테리드 함유 분말이 함께 충전된 경질 캡슐제에 관한 것이다.
