Rice is described that is tolerant/resistant to AHAS/ALS inhibitors because of a plurality of mutations that act synergistically in providing resistance/tolerance to the herbicide. Tolerance/resistance is due to presence of combined mutations in the rice leading to amino acid substitutions (A205V and G654E) in the AHAS/ALS enzyme. Use of the rice for weed control and methods of producing tolerant/resistant rice are also disclosed.
