Qingfeng CHEN,Choong Tat KENG,Yee Joo TAN,Antonio BERTOLETTI
申请号：
US14896239
公开号：
US20160135437A1
申请日:
2014.06.05
申请国别(地区):
US
年份:
2016
代理人:
摘要：
This invention refers to a mouse for human hepatitis studies wherein the mouse has been injected with CD34+ stem cells and wherein the mouse is immunocompromised, as well as a method of manufacturing a mouse model comprising administering CD34+ stem cells as defined herein into an immunocompromised mouse as defined herein. The invention also refers to the use of a mouse as defined for testing the efficiency of putative anti-HBV or anti-HCV drugs or for characterizing changes in viral quasispecies during HBV or HCV infection.
