Method for treating and/or evaluating the human skin, comprising sucking a targeted area of skin up into a chamber to bring the targeted area into contact with a surface present at a recessed position within the chamber so as to, 1) exert at least one of several possible mechanical actions to the targeted area, to include at least one of abrading and puncturing the skin at the targeted area, the abrading resulting from relative movement of the surface relative to the chamber while in contact with the targeted area, and/or repeated movement of the skin against the surface in response to repeating vacuum cycles, and/or 2) apply a composition to the targeted area by transfer from the surface, and/or 3) measure an extent of a contact area between the surface and the targeted area of the skin, and/or 4) measure a contact pressure between the surface and the targeted area of the skin.