INNOVENT BIOLOGICS (SUZHOU) CO. LTD;ELI LILLY AND COMPANY
发明人:
LI, Yiwen,ZHANG, Yi
申请号：
CR20190266
公开号：
CR20190266A
申请日:
2017.12.04
申请国别(地区):
CR
年份:
2019
代理人:
摘要：
The present invention refers to a Class 3 antibody of protein, which contains the immunoglobulin dominance of Mucina and human lymphocyte (TIM-3).Combining them with human PD-1 antibodies, chemotherapy and ionizing radiation, they may be helpful in the treatment of solid tumors and blood tumors, and in the invention of human T-cell immunoglobulin and Mucin-domain antibiotics containing 3 (Tim-3) proteins.And may be useful for treating solid and hematological tumors in combination with anti-human PD-1 antiodis, chemotherapy, and ionizing radiation.La presente invención se refiere a anticuerpos que se fijan a la proteína 3 que contiene el dominio de mucina y el dominio de inmunoglobulina de los linfocitos T humanos (Tim-3), y pueden ser útiles para el tratamiento de tumores sólidos y hematológicos en combinación con anticuerpos anti-PD-1 humana, quimioterapia y radiación ionizanteThe present invention relates to antibodies that bind human T-cell immunoglobulin- and mucin-domain-containing protein-3 (Tim-3), and may be useful for treating solid and hematological tumors in combination with anti-human PD-1 antibodies, chemotherapy, and ionizing radiation.
