Attila Balázs,János Csörgei,Ádám Demeter,Csaba Sánta
申请号:
US14980302
公开号:
US20160220585A1
申请日:
2015.12.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to novel crystalline Form II of 17α-acetoxy-21-methoxy-11β-[4-N,N-dimethylaminophenyl]-19-norpregna-4,9-diene-3,20-dione, (also known as CDB-4124), processes for the preparation thereof and pharmaceutical composition comprising it. Form II can be crystallized from different medium such as esters of C1-C4 alcohols and carboxylic acids, ketones, cyclohexane, acetonitrile, dimethylformamide, dimethyl sulfoxide, water and any mixture thereof.