The present disclosure provides a method for preventing or treating an autism spectrum disorder in a subject in need thereof. The method includes administering to the subject a composition containing a therapeutically effective amount of a benzoic acid salt and a pharmaceutically acceptable excipient thereof. Also provided is a composition for use in preventing or treating an autism spectrum disorder in a subject in need thereof.本揭露提供一種用於預防或治療有需要的個體之泛自閉症障礙之方法,所述方法包括投予該個體包含治療有效量之苯甲酸鹽及其醫藥上可接受之賦形劑。本揭露亦提供一種用於預防或治療有需要的個體之泛自閉症障礙之組成物。