This disclosure provides an intravascular memory metal puncture system and the use thereof. The puncture system comprises a hollow guide tube and a head portion, the hollow guide tube has a spiral structure made of metal and composed of a plurality of spiral coils, the head portion comprises a split-shaped structure capable of opening and closing, as well as a metal spiral hollow tube including a plurality of spiral coils, wherein the split-shaped structure and the metal spiral tube are made of memory metal, and the split-shaped structure is composed of a plurality of tapered petals； when each of tapered petals is closed, the split-shaped structure is a conical structure； when the temperature is T1, the pitch between two adjacent spiral coils in the metal spiral tube is decreased, each of tapered petals in the split-shaped structure is closed； when the temperature is T0, the pitch between two adjacent spiral coils in the metal spiral tube is increased, and each of tapered petals is opened. The puncture system achieves synergistic effect of various components therein, so that it not only can move well in the blood vessels, but also can accurately pierce the blood vessel wall, and achieve effective sampling for biopsy.
