USE OF 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 BETA INHIBITORS

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专利权人:

AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.

发明人:

ALISI, MARIA, ALESSANDRA,CAZZOLLA, NICOLA,GAROFALO, BARBARA,FURLOTTI, GUIDO,MAGARO', GABRIELE,OMBRATO, ROSELLA,MANCINI, FRANCESCA,MAGARO, GABRIELE

申请号：

SG11201403788V

公开号：

SG11201403788VA

申请日:

2013.02.08

申请国别(地区):

SG

年份:

2014

代理人:

摘要：

1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors. The present invention relates to the 1H-indazole-3-carboxamide compounds for use as glycogen synthase kinase 3 beta (GSK-3&bgr；) inhibitors and to their use in the treatment of GSK-3&bgr；-related disorders such as, for example, (i) insulin-resistance disorders； (ii) neurodegenerative diseases； (iii) mood disorders； (iv) schizophrenic disorders； (v) cancerous disorders； (vi) inflammation, (vii) substance abuse disorders； and (viii) epilepsies.

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