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SUBSTITUTED PURINE NUCLEOSIDES, PHOSPHOROAMIDATE AND PHOSPHORODIAMIDATE DERIVATIVES FOR TREATMENT OF VIRAL INFECTIONS
专利权人:
Chris McGuigan
发明人:
Chris McGuigan,Karolina Madela,Claire Bourdin,John Vernachio,Stanley Chamberlain
申请号:
US13988354
公开号:
US20140140955A1
申请日:
2011.12.29
申请国别(地区):
US
年份:
2014
代理人:
摘要:
This invention is directed to novel compounds of formula (I) having the structure (I) wherein U, V, W, Z, R1, X1, X2, and Y are defined herein. The compounds of formula (I) and pharmaceutical compositions containing these compounds are useful in the treatment of viral infections in mammals mediated, at least in part, by a virus in the Flaviviridae family of viruses, in particular hepatitis C virus (HCV).
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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