PROBLEM TO BE SOLVED: To provide a tablet containing silodosin in which chemical stability of silodosin to light is improved, and a generation amount of decomposition products (analog) derived from raw drug is suppressed.SOLUTION: There is provide a dry coated tablet in which only an inner core tablet contains silodosin. It is desirable that the dry coated tablet is an orally disintegrating tablet, and it is desirable that the thickness of an outer layer part of the dry coated tablet is 0.1 mm to 5.0 mm. It is possible to allow the outer layer to contain light-shielding agent, and the light-shielding agent is selected from titanium oxide, yellow iron sesquioxide, iron sesquioxide or the like.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2017,JPO&INPIT【課題】シロドシンを含有する錠剤について、シロドシンの光に対する化学的な安定性を向上させ、原薬由来の分解産物(類縁体)の発生量を抑制すること。【解決手段】 シロドシンが内核錠のみに含有される、有核錠を提供する。前記の有核錠は口腔内崩壊錠であることが望ましく、有核錠の外層部の厚みとしては0.1mm~5.0mmであることが望ましい。外層には遮光剤を含有させることが可能であり、遮光剤は酸化チタン、黄色三二酸化鉄、三二酸化鉄等より選ばれる。【選択図】図1
