Hari Chandana Mulamalla;Ying Huang;Maria Polikandritou Lambros
发明人:
Maria Polikandritou Lambros,Ying Huang,Hari Chandana Mulamalla
申请号:
US14240753
公开号:
US09808425B2
申请日:
2012.09.10
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides pharmaceutical compositions containing a vehicle for the targeted delivery of therapeutic and diagnostic agents for the treatment of hyperproliferative diseases. The targeting component of the vehicle is a cystine molecule that is coupled to the cargo component, which can be either a therapeutic or diagnostic agent or to a nanoparticle composition that contains the therapeutic agent or diagnostic. The invention also provides methods of treating hyperproliferative disorders by targeting hyperproliferative disease cells for the targeted delivery of a therapeutic or diagnostic agent.