Medivation Technologies LLC;FENG Ying;POST Leonard E.;SHEN Yuqiao;RU Yuanbin;WANG Evelyn;YU Karen
发明人:
FENG Ying,POST Leonard E.,SHEN Yuqiao,RU Yuanbin,WANG Evelyn,YU Karen
申请号：
IL25890018
公开号：
IL258900D0
申请日:
2018.04.24
申请国别(地区):
IL
年份:
2018
代理人:
摘要：
Described are methods of treatment of a small cell lung cancer subject expressing Schlafen-11 (SLFN 11) with a Poly (ADP-ribose) polymerases (PARP) inhibitor or a pharmaceutically acceptable salt thereof. Specifically, the method comprising detecting SLFN 11 in a tumor cell sample from the subject, and administering effective amount of a PARP inhibitor, such as talazoparib or the tosylate salt of talazoparib, to the subject.
