CAPPELLI, Andrea,ANZINI, Maurizio,BIAVA, Mariangela,MAKOVEC, Francesco,GIORDANI, Antonio,CASELLI, Gianfranco,ROVATI, Lucio Claudio
申请号：
ES06778144
公开号：
ES2555511T3
申请日:
2006.08.03
申请国别(地区):
ES
年份:
2016
代理人:
摘要：
Compound of formula I: ** Formula ** in which: - the substituent at position 1 of the pyrrole ring is a phenyl, substituted at position 3 and 4 with groups R 'and R ", independently selected from: hydrogen, fluorine, chlorine, bromine, methyl and trifluoromethyl, provided that in a compound of formula I, R 'and R "are not simultaneously trifluoromethyl； - the substituent R1 in position 2 of the pyrrole ring is methyl or ethyl； - the substituent in position 3 of the pyrrole ring is a chain of two carbon atoms, in which the groups X, Y, Z have the following meanings: X is independently selected from hydrogen and hydroxyl (-OH)； Y is a carbonyl group (C>； = O)； Z is alkoxy (-OR3)； - wherein the R3 group is selected from n-propyl, isopropyl, n-butyl, sec-butyl and iso-butyl； - the group R "'is independently selected from hydrogen, methylsulfonyl (-SO2Me) and aminosulfonyl (-SO2NHR2) in which R2 is selected from the group consisting of methyl, ethyl, n-propyl, isopropyl, n-butyl, sec- butyl and iso-butyl； the compounds of formula I may be chiral compounds, the compounds of formula I may exist as individual enantiomers (S or R) or as a mixture of such enantiomers； such enantiomers and their racemic mixtures are included or enantiomer enriched mixtures of compounds of formula I.Compuesto de fórmula I:**Fórmula** en la que: - el sustituyente en la posición 1 del anillo de pirrol es un fenilo, sustituido en la posición 3 y 4 con grupos R' y R", seleccionados independientemente de: hidrógeno, flúor, cloro, bromo, metilo y trifluorometilo, siempre que en un compuesto de fórmula I, R' y R" no sean simultáneamente trifluorometilo； - el sustituyente R1 en la posición 2 del anillo de pirrol es metilo o etilo； - el sustituyente en la posición 3 del anillo de pirrol es una cadena de dos átomos de carbono, en el que los grupos X, Y, Z tienen los siguientes significados: X se selecciona independientemente de hidrógeno e hidroxilo (-OH)； Y es un grupo carbonilo (C>；=O)； Z es alcoxi
