An azatricyclic compound (as represented by formula I) which acts as an inhibitor of fibroblast growth factor receptors (FGFR), as well as a pharmaceutical composition thereof, a preparation method, and a use therefor in the treatment of FGFR-mediated diseases. The azatricyclic compound exerts an effect by means of participating in the regulation of a plurality of processes such as cell proliferation, apoptosis, migration, neovascularization, and the like.本發明關於一種作為纖維母細胞生長因子受體(FGFR)抑制劑的氮雜三環類化合物(如式I所示),及其藥物組合物、製備方法,以及其在治療FGFR介導的疾病中的用途。本發明的氮雜三環類化合物藉由參與調節細胞增殖、凋亡、遷移、新生血管生成等多個過程而發揮作用。