An integrated resuscitation system for use by a rescuer to resuscitate a patient is provided, including: a defibrillation and CPR resuscitation assembly including: a first high-voltage defibrillation electrode; a second high-voltage defibrillation electrode; a compression-sensing element mechanically connected with the first and second electrodes, the compression-sensing element comprising an accelerometer and associated circuitry; and a resuscitation control unit including an internal charge storage capacitor, a microprocessor and associated circuitry configured to be electrically connected to the first and second electrodes and the compression-sensing element and configured to analyze signals generated from the compression-sensing element and at least one of the first electrode and the second electrode to provide resuscitation prompts to the rescuer, wherein the prompts are based at least in part on use of the compression-sensing element by the rescuer.