Embodiments of the invention are directed towards neuro-training devices, systems and methods of use thereof that utilize encoded light and audio signals, singly or in combination, to stimulate the human brain and synchronize brain wave function. Various embodiments further comprise novel auriculotherapy methods. Embodiments of the neuro-training invention generally comprise a human interface device component(s), an electronic file playback device component, and one or more audio/visual (A/V) files for playback by the playback device component. Light and/or audio signals encoded in the A/V files are run (played) by the playback device component and transmitted to the human interface device component(s). The resulting audio and/or light signals received by the human interface device component(s) and the audio and light transmitted and emitted therefrom and received by the user's eyes and ears maximize neuroplasticity—;the brain's ability to reorganize itself by forming new neural connections, resulting in greater brain flexibility and resiliency.