Compounds derived from N - (heteroarilmetil) - 6 - [(2 - heteroarilciclopropil) methoxy] - 4 - pririmidin Amine PDE10 inhibitors； Pharmaceutical Composition and its use for the treatment of a disorder selected from psychotic disorders, delusional, among others.
COX, CHRISTOPHER, D.,DUDKIN, VADIM,KERN, JEFFREY,LAYTON, MARK, E.,RAHEEM, IZZAT, T.
申请号：
CL2014000450
公开号：
CL2014000450A1
申请日:
2014.02.25
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
The present invention is directed to pyrimidine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.COMPUESTOS DERIVADOS DE N-(HETEROARILMETIL)-6-[(2-HETEROARILCICLOPROPIL)METOXI]PRIRIMIDIN-4-AMINA, INHIBIDORES DE PDE10； COMPOSICION FARMACEUTICA； Y SU USO PARA EL TRATAMIENTO DE TRASTORNOS NEUROLOGICOS O PSIQUIATRICOS, SELECCIONADO ENTRE TRASTORNOS PSICOTICOS, DELIRANTES, DE ANSIEDAD, ENTRE OTROS.
