Bacterial minicell therapeutic compositions and methods for targeted delivery of bioactive molecules based on antibodies and Fc-containing targeting molecules
The present application relates to the use of bacterial minicells as targeted delivery agentsandDescribed herein are genetically engineered eubacterial minicells designed to preferentially target and deliver therapeutically relevant agents using a minicell surface coupling molecule capable of binding and displaying antibodies or other Fc-containing targeting moiety fusions and conjugates.