The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided.本發明提供結合FGFR2IIIb之抗體,其中該等抗體為無海藻糖基化抗體。本發明提供包含結合FGFR2IIIb之抗體的組合物,其中該組合物中之該等抗體之至少95%為無海藻糖基化抗體。在一些實施例中,提供治療癌症之方法,其包含投與無海藻糖基化抗FGFR2IIIb抗體。